KOD exo(-) DNA Polymerase /Anti-KOD Hotstart Antibody
KOD DNA polymerase exhibits an excellent elongation capability (approx. 130 bases/sec) and strong 3’→5’ exonuclease activity (proofreading activity). However, its sensitivity and efficiency are subject to interference from the enzyme or template concentration during PCR, due to its strong proofreading activity. KOD exo(-) is a 3’→5’ exonuclease minus mutant developed based on KOD DNA polymerase from a hyperthermophilic Archaeon Thermococcus kodakaraensis.