C-reactive protein is described as an acute phase protein that is involved in the activation of complement, acceleration of phagocytosis, and detoxification of substances released from damaged tissue. CRP is one of the most sensitive indicators of inflammation. In response to an inflammatory stimulus, a rise in CRP may be detected within 6 hours. CRP is a sensitive, non-specific indicator of acute phase reactants. The level of CRP in serum is elevated in patients with arthritis or liver disease such as hepatitis A, hepatitis B, or biliary cirrhosis, and after severe infections such as septic shock.