Methadone (DOLOPHINE®) is a synthetic opioid indicated for the management of pain severe enough to require daily, around-the-clock, long-term opioid treatment and for which alternative treatment options are inadequate. It is a Schedule II substance under the United States Controlled Substances Act for its potential for abuse and risk of dependence.

Methadone is metabolized to a variety of inactive metabolites, including the primary metabolite 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine (EDDP). EDDP is therefore a useful marker in identifying methadone.

The ARK™ EDDP Assay is an immunoassay intended for the qualitative and/or semiquantitative determination of EDDP in human urine at a cutoff concentration of 100 ng/mL and 300 ng/mL.

  • The ARK™ EDDP Assay provides a simple and rapid analytical screening procedure for detecting EDDP
  • Sensitive and specific for detection of EDDP in human urine
  • Low cross-reactivity to Methadone– ensuring patients are taking their medication and there are no positive results due to urine spiking
  • 0 – 1000 ng/mL calibration range; 100 ng/mL and 300 ng/mL cutoffs

ARK™ is a trademark of ARK Diagnostics, Inc.

Calibrator: ARK™ EDDP Calibrator

Control: ARK™ EDDP Control

Product Available in select countries in the following territories:

USA - Not available in all countries. Contact us for availability.


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Ordering Information

Name Size Part Package Insert
ARK™ EDDP Assay R1 1 x 28mL, R2 1 x 14mL 5051-0001-00 N/A
ARK™ EDDP Assay R1 1 x 115mL, R2 1 x 58mL 5051-0001-01 N/A

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